2021
Ciftci, D.*, Martens, C.*, Ghani, V. V., Blanchard, S. C., Politis, A., Huysmans, G. H. M., & Boudker, O. (2021). Linking function to global and local dynamics in an elevator-type transporter. Proceedings of the National Academy of Sciences of the United States of America, 118(49).
doi:10.1073/pnas.2025520118 (*: co-first authors)
Mojr V, Roghanian M, Tamman H, Do Pham DD, Petrová M, Pohl R, Takada H, Van Nerom K, Ainelo H, Caballero-Montes J, Jimmy S, Garcia-Pino A, Hauryliuk V, Rejman. Nonhydrolysable Analogues of (p)ppGpp and (p)ppApp Alarmone Nucleotides as Novel Molecular Tools.D. ACS Chem Biol. 2021 Sep 17;16(9):1680-1691.
doi: 10.1021/acschembio.1c00398
Scholl, D., Sigoillot, M., Overtus, M., Colomer Martinez, R., Martens, C., Wang, Y. Y., Pardon, E., Laeremans, T., Garcia-Pino, A., Steyaert, J., Sheppard, D. N., Hendrix, J., & Govaerts, C. (2021). A Topological Switch in the Cystic Fibrosis Transmembrane Conductance Regulator Modulates Channel Activity and Sensitivity to Disease-Causing Mutation. Nature Chemical Biology.
doi:10.1038/s41589-021-00844-0
Roghanian M, Van Nerom K, Takada H, Caballero-Montes J, Tamman H, Kudrin P, Talavera A, Dzhygyr I, Ekström S, Atkinson GC, Garcia-Pino A, Hauryliuk V. (p)ppGpp controls stringent factors by exploiting antagonistic allosteric coupling between catalytic domains. Mol Cell. 2021 Aug 19;81(16):3310-322.e6.
doi:10.1016/j.molcel.2021.07.026.PMID: 34416138
Jodaitis, L., Van Oene, T., & Martens, C. (2021). Assessing the Role of Lipids in the Molecular Mechanism of Membrane Proteins. International journal of molecular sciences, 22(14).
doi:10.3390/ijms22147267
Kurata T, Brodiazhenko T, Alves Oliveira SR, Roghanian M, Sakaguchi Y, Turnbull KJ, Bulvas O, Takada H, Tamman H, Ainelo A, Pohl R, Rejman D, Tenson T, Suzuki T, Garcia-Pino A, Atkinson GC, Hauryliuk VRelA-SpoT Homolog toxins pyrophosphorylate the CCA end of tRNA to inhibit protein synthesis. Mol Cell. 2021 Aug 5;81(15):3160-3170.e9
doi: 10.1016/j.molcel.2021.06.005
Waeytens J , Mathurin J , Deniset-Besseau A , Arluison V , Bousset L , Rezaei H, Raussens V , Dazzi A . Probing amyloid fibril secondary structures by infrared nanospectroscopy: experimental and theoretical considerations. Analyst. 2021 Jan 4;146(1):132-145.
doi: 10.1039/d0an01545h
Kapetanakis GC, Gournas C, Prévost M, Georis I, André B. Overlapping Roles of Yeast Transporters Aqr1, Qdr2, and Qdr3 in Amino Acid Excretion and Cross-Feeding of Lactic Acid Bacteria. Front Microbiol. 2021 Nov 23;12:752742.
doi: 10.3389/fmicb.2021.752742
Del Alamo D, Govaerts C, Mchaourab HS. AlphaFold2 predicts the inward-facing conformation of the multidrug transporter LmrP. Proteins. 2021 Sep;89(9):1226-1228.
doi: 10.1002/prot.26138
Saidani H, Léonetti M, Kmita H, Homblé F. The Open State Selectivity of the Bean Seed VDAC Depends on Stigmasterol and Ion Concentration. Int J Mol Sci. 2021 Mar 16;22(6):3034.
doi: 10.3390/ijms22063034
Behr M, Speeckaert N, Kurze E, Morel O, Prévost M, Mol A, Adamou NM, Baragé M, Renaut J, Schwab W, El Jaziri M, Baucher M. Leaf necrosis resulting from down-regulation of poplar glycosyltransferase UGT72A2. Tree Physiol. 2021 Dec 3:tpab161.
doi: 10.1093/treephys/tpab161
Vanhaverbeke C, Touboul D, Elie N, Prévost M, Meunier C, Michelland S, Cunin V, Ma L, Vermijlen D, Delporte C, Pochet S, Le Gouellec A, Sève M, Van Antwerpen P, Souard F. Untargeted metabolomics approach to discriminate mistletoe commercial products. Sci Rep. 2021 Jul 9;11(1):14205.
2020
Jia, R*., Martens, C.* #, Shekhar, M., Pant, S., Pellowe, G. G., Lau, A. A., Findlay, H., Harris, N. N., Tajkhorshid, E., Booth, P. P., & Politis, A#. (2020). Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter. Nature communications, 11(1), 6162.
doi:10.1038/s41467-020-20032-3 (*: co-first authors)(#co-corresponding authors)
Tamman H, Van Nerom K, Takada H, Vandenberk N, Scholl D, Polikanov Y, Hofkens J, Talavera A, Hauryliuk V, Hendrix J, Garcia-Pino A. A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes.Nat Chem Biol. 2020 Aug;16(8):834-840.
doi: 10.1038/s41589-020-0520-2
Martens, C*., & Politis, A*. (2020). A glimpse into the molecular mechanism of integral membrane proteins through hydrogen–deuterium exchange mass spectrometry. Protein science.
doi:10.1002/pro.3853 (#co-corresponding authors)
Takada H, Roghanian M, Murina V, Dzhygyr I, Murayama R, Akanuma G, Atkinson GC, Garcia-Pino A, Hauryliuk V. The C-Terminal RRM/ACT Domain Is Crucial for Fine-Tuning the Activation of ‘Long’ RelA-SpoT Homolog Enzymes by Ribosomal Complexes.Front Microbiol. 2020 Feb 28;11:277.
doi: 10.3389/fmicb.2020.00277
Debruycker, V., Hutchin, A., Masureel, M., Ficici, E., Martens, C., Legrand, P., Stein, R. A., Mchaourab, H. S., Faraldo-Gómez, J. J., Remaut, H., & Govaerts, C. (2020). An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity. Nature structural & molecular biology.
Jimmy S, Saha CK, Kurata T, Stavropoulos C, Oliveira SRA, Koh A, Cepauskas A, Takada H, Rejman D, Tenson T, Strahl H, Garcia-Pino A, Hauryliuk V, Atkinson. A widespread toxin-antitoxin system exploiting growth control via alarmone signaling.GC.Proc Natl Acad Sci U S A. 2020 May 12;117(19):10500-10510.
doi: 10.1073/pnas.1916617117.
Blond P, Bevernaegie R, Troian-Gautier L, Lagrost C, Hubert J, Reniers F, Raussens V, Jabin I. Ready-to-Use Germanium Surfaces for the Development of FTIR-Based Biosensors for Proteins. Langmuir. 2020 Oct 13;36(40):12068-12076.
doi: 10.1021/acs.langmuir.0c02681
Yang D, Klebl DP, Zeng S, Sobott F, Prévost M, Soumillion P, Vandenbussche G, Fontaine V. Interplays between copper and Mycobacterium tuberculosis GroEL1. Metallomics. 2020 Aug 19;12(8):1267-1277.
Nguyen HH, Ábrányi-Balogh P, Petri L, Mészáros A, Pauwels K, Vandenbussche G, Keserű GM, Tompa P. Targeting an Intrinsically Disordered Protein by Covalent Modification. Methods Mol Biol. 2020;2141:835-854.
doi: 10.1007/978-1-0716-0524-0_43
Uzureau S, Lecordier L, Uzureau P, Hennig D, Graversen JH, Homblé F, Mfutu PE, Oliveira Arcolino F, Ramos AR, La Rovere RM, Luyten T, Vermeersch M, Tebabi P, Dieu M, Cuypers B, Deborggraeve S, Rabant M, Legendre C, Moestrup SK, Levtchenko E, Bultynck G, Erneux C, Pérez-Morga D. APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin. Pays E.Cell Rep. 2020 Mar 17;30(11):3821-3836.e13.
doi: 10.1016/j.celrep.2020.02.064
Waeytens J, Van Hemelryck V, Deniset-Besseau A, Ruysschaert JM, Dazzi A, Raussens V. Characterization by Nano-Infrared Spectroscopy of Individual Aggregated Species of Amyloid Proteins. Molecules. 2020 Jun 24;25(12):2899.
doi: 10.3390/molecules25122899
Yang D, Vandenbussche G, Vertommen D, Evrard D, Abskharon R, Cavalier JF, Berger G, Canaan S, Khan MS, Zeng S, Wohlkönig A, Prévost M, Soumillion P, Fontaine. Methyl arachidonyl fluorophosphonate inhibits Mycobacterium tuberculosis thioesterase TesA and globally affects vancomycin susceptibility. V.FEBS Lett. 2020 Jan;594(1):79-93.
doi: 10.1002/1873-3468.13555
Bouzghaya S, Amri M, Homblé F. Improvement of Diabetes Symptoms and Complications by an Aqueous Extract of Linum usitatissimum (L.) Seeds in Alloxan-Induced Diabetic Mice. J Med Food. 2020 Oct;23(10):1077-1082.
doi: 10.1089/jmf.2019.0205
Carvalho A, Viaene J, Vandenbussche G, De Braekeleer K, Masereel B, Wouters J, Souard F, Vander Heyden Y, Van Antwerpen P, Delporte C, Mathieu V. A new potential anti-cancer beta-carboline derivative decreases the expression levels of key proteins involved in glioma aggressiveness: A proteomic investigation. Drug Dev Res. 2020 Feb;81(1):32-42.
doi: 10.1002/ddr.21600
2019
Martens, C., Shekhar, M., Lau, A. A., Tajkhorshid, E., & Politis, A. (2019). Integrating hydrogen–deuterium exchange mass spectrometry with molecular dynamics simulations to probe lipid-modulated conformational changes in membrane proteins. Nature Protocols (Print), 14(11), 3183-3204.
Manav MC, Turnbull KJ, Jurėnas D, Garcia-Pino A, Gerdes K, Brodersen DE. The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain. Structure. 2019 Nov 5;27(11):1675-1685.e3.
doi: 10.1016/j.str.2019.08.008
Faull, S. S., Lau, A. M. C., Martens, C., Ahdash, Z., Hansen, K., Yebenes, H., Schmidt, C., Beuron, F., Cronin, N. N., Morris, E. P., & Politis, A. (2019). Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nature communications, 10(1), 3814.
doi:10.1038/s41467-019-11772-y
Talavera A, Tamman H, Ainelo A, Konijnenberg A, Hadži S, Sobott F, Garcia-Pino A, Hõrak R, Loris R. A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT. Nat Commun. 2019 Feb 27;10(1):972.
doi: 10.1038/s41467-019-08865-z
Lau, A. M. C., Ahdash, Z., Martens, C., & Politis, A. (2019). Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry. Bioinformatics, 35(17), 3171-3173.
doi:10.1093/bioinformatics/btz022
Jurėnas D, Van Melderen L, Garcia-Pino A. Mechanism of regulation and neutralization of the AtaR-AtaT toxin-antitoxin system. Nat Chem Biol. 2019 Mar;15(3):285-294.
doi: 10.1038/s41589-018-0216-z
Savocco J, Nootens S, Afokpa W, Bausart M, Chen X, Villers J, Renard HF, Prévost M, Wattiez R, Morsomme P. Yeast α-arrestin Art2 is the key regulator of ubiquitylation-dependent endocytosis of plasma membrane vitamin B1 transporters. PLoS Biol. 2019 Oct 28;17(10):e3000512.
doi: 10.1371/journal.pbio.3000512
Hénault CM, Govaerts C, Spurny R, Brams M, Estrada-Mondragon A, Lynch J, Bertrand D, Pardon E, Evans GL, Woods K, Elberson BW, Cuello LG, Brannigan G, Nury H, Steyaert J, Baenziger JE, Ulens C. A lipid site shapes the agonist response of a pentameric ligand-gated ion channel. Nat Chem Biol. 2019 Dec;15(12):1156-1164.
doi: 10.1038/s41589-019-0369-4
Krammer EM, Prévost M. Function and Regulation of Acid Resistance Antiporters. J Membr Biol. 2019 Oct; 252(4-5):465-481.
doi: 10.1007/s00232-019-00073-6
Sigoillot M, Overtus M, Grodecka M, Scholl D, Garcia-Pino A, Laeremans T, He L, Pardon E, Hildebrandt E, Urbatsch I, Steyaert J, Riordan JR, Govaerts C. Domain-interface dynamics of CFTR revealed by stabilizing nanobodies. Nat Commun. 2019 Jun 14;10(1):2636.
doi: 10.1038/s41467-019-10714-y
Franck T, Aldib I, Zouaoui Boudjeltia K, Furtmüller PG, Obinger C, Neven P, Prévost M, Soubhye J, Van Antwerpen P, Mouithys-Mickalad A, Serteyn D. The soluble curcumin derivative NDS27 inhibits superoxide anion production by neutrophils and acts as substrate and reversible inhibitor of myeloperoxidase. Chem Biol Interact. 2019 Jan 5;297:34-43.
doi: 10.1016/j.cbi.2018.10.008
2018
Martens, C., Shekhar, M., Borysik, A. A., Lau, A. M. C., Reading, E., Tajkhorshid, E., Booth, P. P., & Politis, A. (2018). Direct protein-lipid interactions shape the conformational landscape of secondary transporters. Nature communications, 9(1), 4151.
doi:10.1038/s41467-018-06704-1
Goormaghtigh F, Fraikin N, Putrinš M, Hauryliuk V, Garcia-Pino A, Udekwu K, Tenson T, Kaldalu N, Van Melderen L. Reply to Holden and Errington, “Type II Toxin-Antitoxin Systems and Persister Cells”. mBio. 2018 Sep 25;9(5):e01838-18.
Ahdash, Z., Lau, A. M. C., Martens, C., & Politis, A. (2018). Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry. Journal of Visualized Experiments,(140).
doi:10.3791/57966
Eubelen M, Bostaille N, Cabochette P, Gauquier A, Tebabi P, Dumitru AC, Koehler M, Gut P, Alsteens D, Stainier DYR, Garcia-Pino A, Vanhollebeke B. A molecular mechanism for Wnt ligand-specific signaling. Science. 2018 Aug 7;361(6403):eaat1178.
Jurėnas D, Van Melderen L, Garcia-Pino A. Crystallization and X-ray analysis of all of the players in the autoregulation of the ataRT toxin-antitoxin system. Acta Crystallogr F Struct Biol Commun. 2018 Jul 1;74(Pt 7):391-401.
doi: 10.1107/S2053230X18007914
Roth A, Govaerts C. LmrP from Lactoccoccus lactis: a tractable model to understand secondary multidrug transport in MFS. Res Microbiol. 2018 Sep-Oct;169(7-8):468-477.
doi: 10.1016/j.resmic.2018.07.006
Krammer EM, Gibbons A, Roos G, Prévost M. Molecular mechanism of substrate selectivity of the arginine-agmatine Antiporter AdiC. Sci Rep. 2018 Oct 23;8(1):15607.
doi: 10.1038/s41598-018-33963-1
Nguyen HH, Volkov AN, Vandenbussche G, Tompa P, Pauwels K. In vivo biotinylated calpastatin improves the affinity purification of human m-calpain. Protein Expr Purif. 2018 May;145:77-84.
doi: 10.1016/j.pep.2018.01.002
Blond P, Mattiuzzi A, Valkenier H, Troian-Gautier L, Bergamini JF, Doneux T, Goormaghtigh E, Raussens V, Jabin I. Grafting of Oligo(ethylene glycol)-Functionalized Calix[4]arene-Tetradiazonium Salts for Antifouling Germanium and Gold Surfaces. Langmuir. 2018 May 29;34(21):6021-6027.
doi: 10.1021/acs.langmuir.8b00464
Henry N, Krammer EM, Stengel F, Adams Q, Van Liefferinge F, Hubin E, Chaves R, Efremov R, Aebersold R, Vandenbussche G, Prévost M, Raussens V, Deroo S. Lipidated apolipoprotein E4 structure and its receptor binding mechanism determined by a combined cross-linking coupled to mass spectrometry and molecular dynamics approach. PLoS Comput Biol. 2018 Jun 22;14(6):e1006165.
doi: 10.1371/journal.pcbi.1006165
2017
Reading, E., Hall, Z., Martens, C., Haghighi, T., Findlay, H., Ahdash, Z., Politis, A., & Booth, P. S. L. (2017). Interrogating Membrane Protein Conformational Dynamics within Native Lipid Compositions. Angewandte Chemie, 56(49), 15654-15657.
Jurėnas D, Garcia-Pino A, Van Melderen L. Novel toxins from type II toxin-antitoxin systems with acetyltransferase activity. Plasmid. 2017 Sep;93:30-35.
doi: 10.1016/j.plasmid.2017.08.005
Talavera A, Tamman H, Ainelo A, Hadǽi S, Garcia-Pino A, Hõrak R, Konijnenberg A, Loris R. Production, biophysical characterization and crystallization of Pseudomonas putida GraA and its complexes with GraT and the graTA operator. Acta Crystallogr F Struct Biol Commun. 2017 Aug 1;73(Pt 8):455-462.
doi: 10.1107/S2053230X17009438
Jurėnas D, Chatterjee S, Konijnenberg A, Sobott F, Droogmans L, Garcia-Pino A, Van Melderen L. AtaT blocks translation initiation by N-acetylation of the initiator tRNAfMet. Nat Chem Biol. 2017 Jun;13(6):640-646.
Gournas C, Saliba E, Krammer EM, Barthelemy C, Prévost M, André B. Transition of yeast Can1 transporter to the inward-facing state unveils an α-arrestin target sequence promoting its ubiquitylation and endocytosis. Mol Biol Cell. 2017 Oct 15;28(21):2819-2832.
doi: 10.1091/mbc.E17-02-0104
Troupiotis-Tsaïlaki A, Zachmann J, González-Gil I, Gonzalez A, Ortega-Gutiérrez S, López-Rodríguez ML, Pardo L, Govaerts C. Ligand chain length drives activation of lipid G protein-coupled receptors. Sci Rep. 2017 May 17;7(1):2020.
doi: 10.1038/s41598-017-02104-5
Itkin A, Salnikov ES, Aisenbrey C, Raya J, Glattard E, Raussens V, Ruysschaert JM, Bechinger B. Structural Characterization of the Amyloid Precursor Protein Transmembrane Domain and Its γ-Cleavage Site. ACS Omega. 2017 Oct 9;2(10):6525-6534.
doi: 10.1021/acsomega.7b00619
Mlayeh L, Krammer EM, Léonetti M, Prévost M, Homblé F. The mitochondrial VDAC of bean seeds recruits phosphatidylethanolamine lipids for its proper functioning. Biochim Biophys Acta Bioenerg. 2017 Sep;1858(9):786-794.
doi: 10.1016/j.bbabio.2017.06.005
Carvalho A, Chu J, Meinguet C, Kiss R, Vandenbussche G, Masereel B, Wouters J, Kornienko A, Pelletier J, Mathieu V. Data in support of a harmine-derived beta-carboline in vitro effects in cancer cells through protein synthesis. Data Brief. 2017 May 5;12:546-551.
doi: 10.1016/j.dib.2017.05.006
Govaerts C. Lipids Can Make Them Stick Together. Trends Biochem Sci. 2017 May;42(5):329-330.
doi: 10.1016/j.tibs.2017.03.001
Soubhye J, Chikh Alard I, Aldib I, Prévost M, Gelbcke M, De Carvalho A, Furtmüller PG, Obinger C, Flemmig J, Tadrent S, Meyer F, Rousseau A, Nève J, Mathieu V, Zouaoui Boudjeltia K, Dufrasne F, Van Antwerpen P. Discovery of Novel Potent Reversible and Irreversible Myeloperoxidase Inhibitors Using Virtual Screening Procedure. J Med Chem. 2017 Aug 10;60(15):6563-6586.
doi: 10.1021/acs.jmedchem.7b00285
Valkenier H, Malytskyi V, Blond P, Retout M, Mattiuzzi A, Goole J, Raussens V, Jabin I, Bruylants G. Controlled Functionalization of Gold Nanoparticles with Mixtures of Calix[4]arenes Revealed by Infrared Spectroscopy. Langmuir. 2017 Aug 22;33(33):8253-8259.
doi: 10.1021/acs.langmuir.7b02140
Carvalho A, Chu J, Meinguet C, Kiss R, Vandenbussche G, Masereel B, Wouters J, Kornienko A, Pelletier J, Mathieu V. A harmine-derived beta-carboline displays anti-cancer effects in vitro by targeting protein synthesis. Eur J Pharmacol. 2017 Jun 15;805:25-35.
doi: 10.1016/j.ejphar.2017.03.034
Gau J, Prévost M, Van Antwerpen P, Sarosi MB, Rodewald S, Arnhold J, Flemmig J.J Tannins and Tannin-Related Derivatives Enhance the (Pseudo-)Halogenating Activity of Lactoperoxidase. Nat Prod. 2017 May 26;80(5):1328-1338.
doi: 10.1021/acs.jnatprod.6b00915.
Sidhu A, Segers-Nolten I, Raussens V, Claessens MM, Subramaniam V. Distinct Mechanisms Determine α-Synuclein Fibril Morphology during Growth and Maturation. ACS Chem Neurosci. 2017 Mar 15;8(3):538-547.
doi: 10.1021/acschemneuro.6b00287
2016
Martens, C., Stein, R., Masureel, M., Roth, A., Mishra, S., Dawaliby, R., Konijnenberg, A., Sobott, F., Govaerts, C., & McHaourab, H. (2016). Lipids modulate the conformational dynamics of a secondary multidrug transporter. Nature Structural and Molecular Biology, 23, 8, 744-51.
Egea-Jimenez AL, Gallardo R, Garcia-Pino A, Ivarsson Y, Wawrzyniak AM, Kashyap R, Loris R, Schymkowitz J, Rousseau F, Zimmermann P. Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling. Nat Commun. 2016 Jul 8;7:12101.
Garcia-Pino A, De Gieter S, Talavera A, De Greve H, Efremov RG, Loris R.
An intrinsically disordered entropic switch determines allostery in Phd-Doc regulation. Nat Chem Biol. 2016 Jul;12(7):490-6.
Zorzini V, Mernik A, Lah J, Sterckx YG, De Jonge N, Garcia-Pino A, De Greve H, Versées W, Loris R. Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF. J Biol Chem. 2016 May 20;291(21):10950-60.
Aldib I, Gelbcke M, Soubhye J, Prévost M, Furtmüller PG, Obinger C, Elfving B, Alard IC, Roos G, Delporte C, Berger G, Dufour D, Zouaoui Boudjeltia K, Nève J, Dufrasne F, Van Antwerpen P. Novel bis-arylalkylamines as myeloperoxidase inhibitors: Design, synthesis, and structure-activity relationship study. Eur J Med Chem. 2016 Nov 10;123:746-762.
doi: 10.1016/j.ejmech.2016.07.053
Dawaliby R, Trubbia C, Delporte C, Noyon C, Ruysschaert JM, Van Antwerpen P, Govaerts C. Phosphatidylethanolamine Is a Key Regulator of Membrane Fluidity in Eukaryotic Cells. J Biol Chem. 2016 Feb 12;291(7):3658-67.
doi: 10.1074/jbc.M115.706523
Gallea JI, Sarroukh R, Yunes-Quartino P, Ruysschaert JM, Raussens V, Celej MS. Structural remodeling during amyloidogenesis of physiological Nα-acetylated α-synuclein. Biochim Biophys Acta. 2016 May;1864(5):501-10.
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Moonens K, Gideonsson P, Subedi S, Bugaytsova J, Romaõ E, Mendez M, Nordén J, Fallah M, Rakhimova L, Shevtsova A, Lahmann M, Castaldo G, Brännström K, Coppens F, Lo AW, Ny T, Solnick JV, Vandenbussche G, Oscarson S, Hammarström L, Arnqvist A, Berg DE, Muyldermans S, Borén T, Remaut H. Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori. Cell Host Microbe. 2016 Jan 13;19(1):55-66.
doi: 10.1016/j.chom.2015.12.004
Dawaliby R, Trubbia C, Delporte C, Masureel M, Van Antwerpen P, Kobilka BK, Govaerts C. Allosteric regulation of G protein-coupled receptor activity by phospholipids.Nat Chem Biol. 2016 Jan;12(1):35-9.
doi: 10.1038/nchembio.1960
Krammer EM, Ghaddar K, André B, Prévost M. Unveiling the Mechanism of Arginine Transport through AdiC with Molecular Dynamics Simulations: The Guiding Role of Aromatic Residues. PLoS One. 2016 Aug 2;11(8):e0160219.
doi: 10.1371/journal.pone.0160219
Ambroggio EE, Caruso B, Villarreal MA, Raussens V, Fidelio GD. Reversing the peptide sequence impacts on molecular surface behaviour. Colloids Surf B Biointerfaces. 2016 Mar 1;139:25-32.
doi: 10.1016/j.colsurfb.2015.12.008
Urbina P, Bersch B, De Angelis F, Derfoufi KM, Prévost M, Goormaghtigh E, Vandenbussche G. Structural and Functional Investigation of the Ag(+)/Cu(+) Binding Domains of the Periplasmic Adaptor Protein SilB from Cupriavidus metallidurans CH34. Biochemistry. 2016 May 24;55(20):2883-97.